Antimicrobial Agent
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Protocol to Experiment Antibacterial Agents Originated from Natural Products.Antimicrobial Agent 2022. 2. 27. 16:25
These days, I am studying the antimicrobial activity of phytochemicals. In prior of this, I should know an adequate protocol to investigate natural product originated antimicrobial agents. Therefore, I found a paper (Anti-infective potential of natural products: How to develop a stronger in vitro ‘proof-of-concept’) giving detail about it. It is basically about how to choose plants, extraction, ..
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Antibiofilm ability of harmaline and norharmane from Peganum harmalaAntimicrobial Agent 2022. 2. 19. 18:58
As the day goes, the problem with antibiotic-resistant bacteria is getting serious and usually, they are apt to form biofilms which mean they are serious pathogens. So many people have been trying to find an efficient way to deal with them. There are many other ways to deal with antibiotic-resistant bacteria and one interesting way to fight against them is by inhibiting their biofilm formation. ..
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Brief Review about Antibiotics and Cell WallAntimicrobial Agent 2021. 7. 4. 22:55
Antibiotic is a kind of drug that kills bacteria. Since penicillin was discovered by Alexander Fleming, human beings got able to cure bacterial disease(including getting infected) more easily. However, due to abuse and over using it, it caused emergence of antibiotic resistant bacteria like MRSA(methicilline resistant Staphylococcus aureus). Anyway, at this writing, I’m going to discuss about 1)..
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After reading “Antimicrobial activity of flavonoids extracted from bergamot(Citrus bergamia Risso) peel, a byproduct of the essential oil industry”Antimicrobial Agent 2021. 7. 3. 11:42
Before I went on my vaccation, I read this paper and I found some interesting information about flavonoids. The result of this study is that flavonoids from bergamot have antimicrobial activty agains Gram–negative bacteria but also against other microorganisms including Gram-positive bacteria, fungi and viruses. At the intro of this paper, it says that most of flavonoids are generally glycosylat..
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A Comparison of the Antibacterial and Antifungal Activities of Thiosulfinate Analogues of AllicinAntimicrobial Agent 2021. 5. 24. 23:41
As I said at my preposting, allicin reacts with thiol(-SH) groups and this can inactivate essential proteins such as enzymes and others. This kind of character leads to antimicrobial activity and there were some experiments to prove it. According to many papers, allicin’s antimicrobial activity is due to the thiosulfinate group binding on the essential part of the proteins. This paper had experi..
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Antimicrobial Effect of ThiosulfinatesAntimicrobial Agent 2021. 5. 23. 22:56
Allicin reacts with –SH groups of cellular proteins. Before, it used to be thought that they could react only with cysteine but not with other amino acids. Because of their –S(O)-S- group, which generally reacts with the SH group of cellular proteins to generate mixed disulfides. However, there are evidence that allicin and other thiosulfinates also react with non –SH amino acids. At this point,..
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How to Use Phytochemicals as Antimicrobial AgentsAntimicrobial Agent 2021. 4. 29. 22:52
These days, I read some papers about using phytochemicals as antimicrobial agents during the isolation period after my furlough(I'm currently doing my duty in ROKAF). So, I've read some paper about it('cuz I was so bored that I almost died lol) and I found out that antibiotic resistant bacteria can affect hugely in our lives. Compared to the past, frequency of there emergence is sky rocketing an..